Grant for LXR Project

Acelot has been awarded a prestigious SBIR Grant from the National Institutes of Health for the discovery of novel LXR-based leads for Alzheimer’s disease based on Acelot’s computer-based JPS method.

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Patent Granted

U.S. patent 9,218,460 on the JPS method has been granted with Ambuj Singh as one of the inventors. Acelot holds an exclusive license for this patent.

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Publication on LRRK2 Project

Acelot co-authored an article in Bioorganic & Medicinal Chemistry Letters on the use of its unique JPS technology for the discovery of novel LRRK2 inhibitors for the treatment of Parkinson’s disease.

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Acelot at BIO 2014

Acelot will attend the 2014 BIO International Convention on June 23-26 in San Diego. We are looking forward to meet with you at the BIO Business Forum.

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Grant for Drug Discovery Platform

Acelot has been awarded a prestigious SBIR Grant from the National Science Foundation to build a cloud-based, “learning” drug discovery platform based on Acelot’s unique graph-based mining algorithms.

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Novel Amyloid Oligomer Blockers Discovered

Acelot has identified a diverse set of lead candidates that have the potential to block the toxic effects of soluble amyloid oligomers on nerve cells. These compounds have shown nanomolar potency in a recent phenotypic assay that measures the “health” of neurons.

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Grant for RXR Project

Acelot has been awarded a prestigious SBIR Phase I Grant from the NIH to identify novel RXR agonists for Alzheimer’s Disease. Acelot is partnering with the Neuroscience Research Institute at UC Santa Barbara to discover and characterize new drug candidates.

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